Abstract
This article will argue that future outer space flight may cause micro-evolutionary changes to
the human body, and will explain the nature of these changes from the point of view of evolutionary
medicine. Initial adaptation will be protracted with considerable problems to long term outer space
flight, especially inter-generational outer space travellers. The authors examine possible neurobehavioural
and psycho-social possibilities for long term outer space travellers due to separation
from the biotic environment in which humans have evolved. The authors also develop novel ideas in
reducing possible deleterious micro-evolutionary effects during long term outer space flight.
Keywords: Nature, neuro-behavioural, neuro-hormonal regulation, Heraclitean motion, symbolic
cognition, future human population
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